Shape-selective remobilization of microparticles in a mesh-based DEP filter at high throughput

In numerous of studies, dielectrophoresis (DEP) has proven that its high selectivity and versatility make it a promising separation technique in variety fields. So far, however, only few processes the bioanalytics have made to commercial use. One main challenges is achieve technically relevant throughput while maintaining selectivity. We present novel approach mesh-based DEP filter with ordered field disturbing structures potential for upscaling because low-cost commercially available materials are used. this filter, we firstly trap mixture particles then selectively remobilize them via frequency shift, which allows multidimensional separation. Shape-selective demonstrated using ellipsoidal spherical polystyrene particles, first established microchannels subsequently filter. Hence, were trapped at flow rates up 120mLh−1 remobilized according their shape. These results pave way high-throughput multitarget separations single scalable device.